The most comprehensive and luxurious spa on Isla Mujeres is located inside the resort of Zoetry Villa Rolandi. Their wellness center offers a range of treatments including deep tissue massage, exfoliating facials, and waxing. The hotel is located in the Sac Bajo area on the Cancun side of the island, where many luxury accommodations are situated. The highlight here has to be the Thalassotherapy treatments which use seawater, marine mud, and seaweed to infuse the skin with nutrients. With every treatment you can also take full advantage of the spa’s facilities including the saltwater pool and steam room.